Douwe A. J. Grundel

The paper shows that accessible Gibbs energy at metabolic activation limits long-term cell growth by constraining metabolic reorganization and ATP production.

The paper develops a computational model of fission yeast metabolism to explore resource allocation and metabolic strategies under different glucose conditions.

The paper develops a simulation tool to study how cells self-organize dynamic spatial patterns through cellular communication, identifying core architectures and a three-stage process.