Author

Yara Y. Hassan

The Ohio State UniversityORCID 0009-0005-6309-1573Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2

Frequent Co-Authors

Amal O. AmeriD· 2 shared Asmaa BadriD· 2 shared Gauruv A. Gupta· 2 shared Heba M. AmeriD· 2 shared Mohamed M. ShamseldiniD· 2 shared Mostafa M. EltobgyiD· 2 shared Owen D. Whitham· 2 shared Sarah E. Faber· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

Amal O. AmerORCID

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2 papers

Recent·Most cited

MicrobiologyJCI InsightPeer-reviewedSep 21, 2026

Caspase-11 Mediated Hyperinflammation Impairs CD8⁺ T Cell Immunity and Viral Clearance in Severe SARS-CoV-2 Infection

Mostafa M. Eltobgy, Mohamed M. Shamseldin, Owen D. Whitham…·Amal O. Amer

This study shows that Caspase-11 worsens severe SARS-CoV-2 by increasing inflammation and reducing CD8 T-cell immunity, but its removal improves viral clearance and survival.

1 citation

mouseexperimental assay

𝕏 PostBluesky

ImmunologybioRxivPreprintAug 20, 2026

Gelsolin protects mitochondria and regulates inflammation during Legionella pneumophila infection

Owen D. Whitham, Mostafa M. Eltobgy, Mohamed M. Shamseldin…·Amal O. Amer

This study shows that gelsolin protects against Legionella pneumophila infection by maintaining mitochondrial health, reducing inflammation, and supporting neutrophil function.

DOI 10.64898/2026.08.17.745205

mouseexperimental assay

𝕏 PostBluesky