Author

Danna Lee

Cambridge CollegeORCID 0009-0004-4111-9195Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

A.L.W. KleinhenziD· 1 shared Atip LawanprasertiD· 1 shared Axel TruedsoniD· 1 shared Daniel Chu· 1 shared Daniel JonesiD· 1 shared David N. NguyeniD· 1 shared Hao WuiD· 1 shared Jakub WiktoriD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioengineering

A.L.W. KleinhenzORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

A lipid nanoparticle platform for high yield CRISPR-targeted homology directed repair enables fully non-viral CAR T cell generation

Joy J. Chen, Atip Lawanprasert, A.L.W. Kleinhenz, Mehar G. D. Namala, Daniel Chu, York Tang, Valentine Lindarto, Michael Launspach, Danna Lee, Hao Wu, Niren Murthy, David N. Nguyen

This paper develops a lipid nanoparticle (LNP) platform for non-viral CRISPR-mediated homology directed repair (HDR) to generate CAR T cells with improved efficiency and reduced toxicity compared to electroporation.

bioRxiv · Aug 5, 2026 · PreprintBioengineering

Molecular kinetics dictate population dynamics in CRISPR-based plasmid defense

Luke Richards, Danna Lee, Jakub Wiktor, Axel Truedson, Johanna Cederblad, Daniel Jones

The paper uses time-lapse imaging to study CRISPR-Cas dynamics in bacterial plasmid defense, finding that Cascade provides partial plasmid clearance with tradeoffs between clearance and cell growth.

Proceedings of the National Academy of Sciences · Mar 30, 2026Peer-reviewedMolecular Biology