ImmunologybioRxivPreprint
Profiling Nucleotide Signalling Pathways and STING Agonist Activity with a Nucleotide Library
Indra Bekere, Rupert Öllinger, Marie Rose Schrimpf…·Carina C. de Oliveira Mann
The paper identifies 27 cyclic dinucleotides that activate STING, showing STING's preference for 2'3'-linked nucleotides and its ability to respond to non-hydrolysable isomers.
DOI 10.1101/2025.11.11.687896