Cancer BiologyMolecular CarcinogenesisPeer-reviewed
Metabolism-focused CRISPR screen unveils Mitochondrial Pyruvate Carrier 1 as a critical driver for PARP inhibitor resistance in lung cancer
Takashi Furusawa, Renzo Cavero, Yue Liu…·Urbain Weyemi
The paper identifies MPC1 as a key driver of PARP inhibitor resistance in NSCLC lung cancer through a metabolism-focused CRISPR screen.
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