Author

James D Begando

ORCID 0009-0005-8927-9144Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:metagenomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Eric M. PearlmaniD· 2 shared George DubyakiD· 2 shared Michaela Ellen MarshalliD· 2 shared Angela Lackner· 1 shared Arne RietschiD· 1 shared Camille AndréiD· 1 shared Emma KundracikiD· 1 shared Jolynn Tran Chau· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMicrobiology

Eric M. PearlmanORCID

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2 papers

Recent·Most cited

MicrobiologyInfection and ImmunityPeer-reviewedJul 22, 2026

Pseudomonas aeruginosa Exotoxin A is not essential for corneal disease severity or bacterial survival

James D Begando, Michaela Ellen Marshall, Emma Kundracik…·Eric M. Pearlman

The paper shows that Exotoxin A is not essential for bacterial survival or corneal disease severity in P. aeruginosa keratitis in mice.

DOI 10.1128/iai.00165-26

mouseexperimental assay

𝕏 PostBluesky

MicrobiologybioRxivPreprintDec 14, 2025

Alpha hemolysin polymorphisms in methicillin-resistant Staphylococcus aureus clinical isolates regulate ADAM10-dependent neutrophil IL-1 beta secretion

Karl Liboro, Jolynn Tran Chau, James D Begando…·Eric M. Pearlman

The paper shows that Hla polymorphisms in MRSA strains affect ADAM10-dependent neutrophil IL-1β secretion and corneal disease severity.

2 citations

𝕏 PostBluesky