Maxwell McDermott

The paper compares the ability of different Orai isoforms to promote NFAT activation and transcription, finding Orai1α and Orai1β are more potent than Orai2 and Orai3.

This study shows that CTR1-mediated copper uptake is essential for pTH17 cell differentiation and function in autoimmune disease by linking copper homeostasis to metabolic and epigenetic regulation.

This study identifies Treg cells and IFN-γ-producing Th1 cells as key drivers of Sjögren's Syndrome pathogenesis using a mouse model and single-cell transcriptomics.

This study uses single-cell transcriptomics to identify altered activation states of B and T lymphocytes in Sjogren's Disease patients compared to controls.

This study evaluates the reward liability of MS15203, a GPR171 ligand, in mice and finds it produces minimal reward-related behavior.