Stefan Feske

The paper compares the ability of different Orai isoforms to promote NFAT activation and transcription, finding Orai1α and Orai1β are more potent than Orai2 and Orai3.

This study shows that CTR1-mediated copper uptake is essential for pTH17 cell differentiation and function in autoimmune disease by linking copper homeostasis to metabolic and epigenetic regulation.

This study identifies Treg cells and IFN-γ-producing Th1 cells as key drivers of Sjögren's Syndrome pathogenesis using a mouse model and single-cell transcriptomics.

This study identifies Kir6.1 as a key regulator of natural killer cell development in mice, showing its expression in mature NK cells and its role in NK-cell differentiation.

This study uses single-cell transcriptomics to identify altered activation states of B and T lymphocytes in Sjogren's Disease patients compared to controls.

This study shows that loss of STIM1 and STIM2 in salivary glands reduces ANO1 function and saliva production but does not cause Sjogren's disease, suggesting a link between SOCE and TLR8 signaling.

This study shows that neurotransmitter signaling via SLN-mediated calcium regulation determines sweat gland stem cell fate during development.