Author

David Köhler

University of BonnORCID 0009-0006-0027-4046Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:dimensionality reduction· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Achim TreschiD· 1 shared Chrysa NikopoulouiD· 1 shared Matthias C. SchmidiD· 1 shared Niklas KleinenkuhneniD· 1 shared Peter TessarziD· 1 shared Till BaariD· 1 shared Vangelis KondylisiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Achim TreschORCID

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintOct 12, 2023

Dimension Reduction by Spatial Components Analysis Improves Pattern Detection in Multivariate Spatial Data

Niklas Kleinenkuhnen, David Köhler, Till Baar…·Achim Tresch

The paper introduces SPACO, a method for dimension reduction in spatial transcriptomics data that improves pattern detection by maximizing Moran's I and outperforms PCA.

DOI 10.1101/2023.10.12.562016

spatial transcriptomicsstatistical model

𝕏 PostBluesky