Matthias C. Schmid

This study finds that paternal exposure to ionizing radiation increases clustered de novo mutations in offspring, suggesting cDNMs as a transgenerational biomarker.

The paper introduces SPACO, a method for dimension reduction in spatial transcriptomics data that improves pattern detection by maximizing Moran's I and outperforms PCA.

GenoGAM improves ChIP-seq differential occupancy analysis by using generalized additive models to avoid subjective binning, increasing sensitivity while controlling type I error.