Author

Daniel McGuire

Nanostring Technologies (United States)ORCID 0009-0006-0286-9625Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 3

Signature Assays, Organisms & Methods

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Assay:spatial transcriptomics· 3 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Ali ShojaieiD· 2 shared Ana Gabriela VasconcelosiD· 2 shared Patrick J. DanaheriD· 2 shared Andrew GrootskyiD· 1 shared Dwayne L. Dunaway· 1 shared Erin PiazzaiD· 1 shared Evelyn MetzgeriD· 1 shared Jon WakefieldiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersGenomics

Ali ShojaieORCID

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3 papers

Recent·Most cited

GenomicsbioRxivPreprintJul 23, 2025

Accounting for Spatial Correlation in Graphical Analysis of SpatialTranscriptomics Data

Ana Gabriela Vasconcelos, Patrick J. Danaher, Daniel McGuire…·Ali Shojaie

The paper introduces SpaceDecorr, a method to reduce false-positive correlations in spatial transcriptomics data by adjusting for spatial dependencies and technical artifacts.

3 citations

spatial transcriptomicsstatistical model

𝕏 PostBluesky

GenomicsbioRxivPreprintNov 27, 2024

Sub-cellular Imaging of the Entire Protein-Coding Human Transcriptome (18933-plex) on FFPE Tissue Using Spatial Molecular Imaging

Rustem Khafizov, Erin Piazza, Yi Cui…·Joseph Beechem

This paper introduces a high-plex spatial molecular imaging technique capable of sub-cellular transcriptome analysis of FFPE tissues, achieving whole transcriptome coverage with high resolution and minimal dissociation bias.

19 citations

humanspatial transcriptomics

𝕏 PostBluesky

GenomicsbioRxivPreprintAug 2, 2024

Differential Expression Analysis for Spatially Correlated Data

Ana Gabriela Vasconcelos, Daniel McGuire, Noah Simon…·Ali Shojaie

The paper addresses challenges in differential expression analysis of spatial transcriptomics data by mitigating segmentation errors and accounting for spatial correlation, reducing false discoveries.

10 citations

spatial transcriptomicsstatistical model

𝕏 PostBluesky