Sub-cellular Imaging of the Entire Protein-Coding Human Transcriptome (18933-plex) on FFPE Tissue Using Spatial Molecular Imaging
Rustem Khafizov, Erin Piazza, Yi Cui, Michael J. Patrick, Evelyn Metzger, Daniel McGuire, Dwayne L. Dunaway, Patrick J. Danaher, Margaret L. Hoang, Andrew Grootsky, Megan E. Grout, Shanshan He, Rachel Liu, Michael McKean, Michael Rhodes, Joseph Beechem
This paper introduces a high-plex spatial molecular imaging technique capable of sub-cellular transcriptome analysis of FFPE tissues, achieving whole transcriptome coverage with high resolution and minimal dissociation bias.
bioRxiv · Nov 27, 2024 · PreprintGenomics