Ryan P. Seaman

The paper introduces a tissue-clearing framework and mesoSPIM-ultra system for large-scale single-neuron tracing in cleared mouse tissue.

This study shows that intermittent fasting improves muscle health and extends lifespan in both sexes of African turquoise killifish, with sex-specific molecular and cellular changes.

This paper shows that SGLT2 inhibition reduces age-related vascular rarefaction and preserves renal function in African turquoise killifish.

This study shows connective-tissue cells are essential for axolotl limb regeneration, making up 75% of blastema cells and requiring specific signaling for regeneration.

The paper shows that vertebral segmentation during axolotl tail regeneration occurs via a buckling instability mechanism, distinct from the somite-based process in embryonic development.