Dunja Knapp

The paper investigates how scaling of signaling pathways affects adult organ regeneration, finding that mismatched scaling of SHH and Wnt9a signaling prevents digit regeneration in large blastemas.

The paper investigates morphogen scaling mechanisms in axolotl limb regeneration, showing static scaling ensures proportional growth while dynamic scaling does not.

This study shows connective-tissue cells are essential for axolotl limb regeneration, making up 75% of blastema cells and requiring specific signaling for regeneration.

This study shows that cellular senescence promotes progenitor cell expansion during axolotl limb regeneration by creating a pro-proliferative niche and modulating Wnt signaling.

The paper identifies conserved notochord-specific enhancers of Brachyury/T/TBXT in vertebrates and shows their role in notochord expression and development.

The paper identifies segment-specific chromatin states at homeoprotein loci in axolotl limb segments, showing how positional information is encoded for regeneration.

The paper identifies Tig1 as a regulator of proximo-distal identity during salamander limb regeneration through single-cell RNAseq analysis.

This study examines the post-embryonic development and aging of the appendicular skeleton in axolotls, showing continuous ossification and cellular changes throughout life.

The paper identifies a conserved regulatory program driving lateral plate mesoderm emergence across chordates using zebrafish and comparative analysis.