Author

Amélie Zachayus

Centre National de la Recherche ScientifiqueORCID 0009-0006-1240-7942Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Clémence Elly· 2 shared Emmanuel CompeiD· 2 shared Frédéric CoiniD· 2 shared Jean‐Marc EglyiD· 2 shared Max CigrangiD· 2 shared Philippe Catez· 2 shared Pietro BericoiD· 2 shared Carmen CuevasiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersCancer Biology

Clémence Elly

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedJan 8, 2025

Novel synthetic ecteinascidins exhibit potent anti-melanoma activity by suppressing super-enhancer-driven oncogenic transcription

Max Cigrang, Julian Obid, Maguelone Nogaret…·Frédéric Coin

This study shows novel synthetic ecteinascidins effectively treat melanoma by inhibiting super-enhancer-driven oncogenic transcription, even in resistant models.

16 citations

humanbulk RNA-seq

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Molecular BiologyNature CommunicationsPeer-reviewedJan 20, 2023

Active mRNA degradation by EXD2 nuclease elicits recovery of transcription after genotoxic stress

Jérémy Sandoz, Max Cigrang, Amélie Zachayus…·Frédéric Coin

The paper shows that EXD2 nuclease degrades nascent mRNAs during genotoxic stress, enabling transcription recovery after DNA repair.

9 citations

humanbulk RNA-seq

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