Author

John Leland Booth

The Francis Crick InstituteORCID 0009-0006-2031-1924Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

Alireza Alidoust· 1 shared André Arashiro PulscheniD· 1 shared Ari SatanowskiiD· 1 shared Averi Bates· 1 shared Chongle PaniD· 1 shared Christelle SoudyiD· 1 shared Dongyu Wang· 1 shared Erika Alden DeBenedictisiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Alireza Alidoust

Mutual co-authors in cluster

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2 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedMar 24, 2026

Continuous evolution of a halogenase enzyme with improved solubility and activity for sustainable bioproduction

André Arashiro Pulschen, Justin Booth, Ari Satanowski…·Erika Alden DeBenedictis

This paper evolves a halogenase enzyme to improve solubility and activity, enabling higher yields of halogenated compounds for sustainable bioproduction.

3 citationstop 4%

proteomicsdeep learning

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BioinformaticsbioRxivPreprintJun 26, 2024

Nanopore Direct RNA Sequencing Reveals Virus-Induced Changes in the Transcriptional Landscape in Human Bronchial Epithelial Cells

Dongyu Wang, John Leland Booth, Wenxin Wu…·Susan J. Schroeder

This study uses nanopore direct RNA sequencing to identify epitranscriptomic changes in human bronchial epithelial cells exposed to influenza virus, revealing alterations in m6A methylation and pseudouridylation of immune-related genes.

1 citation

humanlong-read sequencing

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