Author

Josette V. Medicielo

Chan Zuckerberg Biohub San FranciscoORCID 0009-0006-2509-5300Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Abigail Leigh GlascockiD· 1 shared Amy L. KistleriD· 1 shared Andreas S. PuschnikiD· 1 shared Andrew L. Markhard· 1 shared Brian C. DeFeliceiD· 1 shared Cristina M. TatoiD· 1 shared Duo PengiD· 1 shared Eric WaltariiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

Abigail Leigh GlascockORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintJan 9, 2025

Genome-wide CRISPR knockout screening with viral replicons for identification of host factors involved in viral replication

Karen W. Cheng, Madhura Bhave, Andrew L. Markhard…·Amy L. Kistler

This paper develops a CRISPR knockout screening method using viral replicons to identify host factors essential for viral replication, successfully identifying known and novel genes for dengue, chikungunya, and Ebola viruses.

1 citation

CRISPR screenexperimental assay

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GenomicsbioRxivPreprintAug 1, 2023

Evolutionary genomics identifies host-directed therapeutics to treat intracellular bacterial infections

Josette V. Medicielo, Eric Waltari, Abigail Leigh Glascock…·Vida Ahyong

This paper uses evolutionary genomics to identify host metabolic pathways critical for intracellular bacterial survival, validating them through in vitro assays and metabolomics.

3 citations

bacteria (other)metabolomics

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