Amy L. Kistler

This study uses a dengue replicon model to show how host pathways are rewired to support persistent RNA replication without stress responses.

This paper develops a CRISPR knockout screening method using viral replicons to identify host factors essential for viral replication, successfully identifying known and novel genes for dengue, chikungunya, and Ebola viruses.

The paper identifies a novel bandavirus as the likely cause of a 2020 black vulture mortality event using metagenomic sequencing.

The paper integrates multi-omic data to identify genetic and microbiome factors associated with severe COVID-19, independent of ancestry and social factors.

The paper identifies a SARS-CoV-2 N gene polymorphism that reduces RT-PCR assay sensitivity and emphasizes the need for multi-target testing.

This paper develops a high-throughput method to generate host and pathogen genomic data from single nasopharyngeal swabs of COVID-19 patients.

The paper explores the ambigrammatic sequences in narnaviruses, showing that codon alignment allows for stop codon elimination in the reverse strand through synonymous substitutions, suggesting a mechanism for de novo gene creation.

The paper introduces MTK, a toolkit for rapid modular DNA circuit assembly in mammalian cells, demonstrating its use in constructing an Ebola virus replication complex circuit.