Pharmacoproteomic profiling identifies secreted markers for aberrant drug action
Sascha Knecht, Mathias Kalxdorf, Johanna Korbeń, Toby Mathieson, Daniel C. Sévin, Bernhard Küster, Richard Kasprowicz, Melanie Z. Sakatis, H. Christian Eberl, Marcus Bantscheff
The paper uses proteomics to identify secreted markers linked to drug-induced liver injury and adverse drug reactions by analyzing the secretome of hepatocytes exposed to various drugs.
bioRxiv · Oct 16, 2024 · PreprintPharmacology & Toxicology