Daniel C. Sévin

The paper uses proteomics to identify secreted markers linked to drug-induced liver injury and adverse drug reactions by analyzing the secretome of hepatocytes exposed to various drugs.

The paper introduces PRISM-MS, a method for fast single-cell MALDI imaging of low-mass metabolites, and demonstrates its application in analyzing metabolome changes in LPS-stimulated microglial cells.

The paper shows how species in gut bacterial communities can survive or go extinct based on resource availability and metabolic interactions, identifying emergent survival and community-driven extinctions.

This study analyzes the adaptability and robustness of Mycoplasma pneumoniae's central carbon metabolism using metabolomics data and a dynamic model, identifying key control hubs.