Leah Sadr

The paper introduces KINESIS, a nanoelectrode array for label-free, high-resolution potassium sensing in single human iPSC-derived cardiomyocytes, showing distinct potential shifts in response to caffeine and ouabain.

This study shows nanoscale membrane curvature and nuclear deformation regulate mechanotransduction by modulating YAP/TAZ nuclear localization through biophysical modeling and experiments.

This study shows that engineered nanotopographies create temporary nuclear membrane openings, enabling molecular exchange without cell penetration.