Author

Samaneh Samiei

RWTH Aachen UniversityORCID 0009-0006-6845-3139Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:batch correction / integration· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Christoph KuppeiD· 2 shared Ivan G. CostaiD· 2 shared Mehdi JoodakiiD· 2 shared Aitor AguirreiD· 1 shared Alex A. ZhavoronkoviD· 1 shared Anna-Maria VllahoiD· 1 shared Anne LoftiD· 1 shared Annelotte VosiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Christoph KuppeORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintFeb 14, 2026

Polyploid cardiomyocytes define disease-specific transcriptional states in the mammalian heart

Paul Kießling, Mehdi Joodaki, Daryna Pikulska…·Christoph Kuppe

This study identifies polyploid cardiomyocytes as disease-specific transcriptional states in the mammalian heart and suggests targeting them for heart failure treatment.

5 citations

humanrat

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BioinformaticsBriefings in BioinformaticsPeer-reviewedAug 31, 2025

PILOT-GM-VAE: Patient-Level Analysis of single cell Disease Atlas with Optimal Transport of Gaussian Mixture Variational Autoencoders

Mehdi Joodaki, Mina Shaigan, Samaneh Samiei…·Ivan G. Costa

PILOT-GM-VAE analyzes single cell disease atlases to perform sample-level clustering, trajectory inference, and batch correction using Gaussian Mixture Variational Autoencoders with optimal transport.

DOI 10.1093/bib/bbaf547

humanscRNA-seq

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