Author

Alazne R. Unanue

Consejo Superior de Investigaciones CientíficasORCID 0009-0006-6927-9996Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Approach:experimental assay· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Antonio Alcamı́iD· 3 shared Bruno HernáeziD· 3 shared Alasdair J. M. HoodiD· 2 shared Carlos Maluquer de MotesiD· 2 shared Lucy EkeiD· 2 shared Rebecca P. SumneriD· 2 shared Ailish EllisiD· 1 shared Ana Moraga-QuintanillaiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersMicrobiology

Antonio Alcamı́ORCID

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintJun 9, 2026

Non-cyclic dinucleotide STING agonists abrogate MPXV infection

Lucy Eke, Alazne R. Unanue, Alasdair J. M. Hood…·Rebecca P. Sumner

The paper shows non-cyclic dinucleotide STING agonists effectively suppress MPXV infection by bypassing poxin-mediated inhibition, leading to reduced viral replication and improved survival in mice.

DOI 10.64898/2026.06.08.730963

humanmouse

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MicrobiologybioRxivPreprintSep 22, 2025

Enhanced mouse virulence of mpox virus clade Ib over clade IIb despite genomic changes caused by human-to-human transmission

Alazne R. Unanue, Rocío Martín, Carolina Sánchez…·Bruno Hernáez

This study compares the virulence of mpox virus clade Ib and IIb, finding clade Ib is more virulent in mice despite genomic changes from human-to-human transmission.

DOI 10.1101/2025.09.22.677787

mouseexperimental assay

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MicrobiologybioRxivPreprintFeb 27, 2025

Attenuation of the 2022 global outbreak monkeypox virus relative to its clade IIb ancestor

Rebecca P. Sumner, Lucy Eke, Bruno Hernáez…·Carlos Maluquer de Motes

This study compares a 2022 MPXV lineage B.1 virus with its clade IIb ancestor A.1, showing attenuated phenotypes including reduced virulence and immune evasion.

5 citations

humanmouse

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