Author

Hongbo Wen

Children's Hospital of PhiladelphiaORCID 0009-0006-7703-7823Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

David B. FrankiD· 2 shared Lisa R. YoungiD· 2 shared Maureen Peers de NieuwburghiD· 2 shared MinQi Lu· 2 shared Prashant ChandrasekaraniD· 2 shared Sylvia N. MichkiiD· 2 shared Annabelle Jin· 1 shared Aravind SivakumariD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersDevelopmental Biology

David B. FrankORCID

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2 papers

Recent·Most cited

Developmental BiologybioRxivPreprintMay 21, 2023

Endodermal BRD4 mediates epithelial-mesenchymal crosstalk during lung development

Derek C. Liberti, Hongbo Wen, Kwaku K. Quansah…·David B. Frank

This study shows that BRD4 in endodermal cells is crucial for lung development by facilitating epithelial-mesenchymal crosstalk, proper lineage allocation, and branching morphogenesis.

1 citation

mousebulk RNA-seq

𝕏 PostBluesky

Developmental BiologybioRxivPreprintApr 30, 2022

A CXCL12 morphogen gradient uncovers lung endothelial heterogeneity and promotes distal vascular growth

Prashant Chandrasekaran, Nicholas M. Negretti, Aravind Sivakumar…·David B. Frank

The paper identifies a CXCL12 morphogen gradient in developing pulmonary vasculature, revealing endothelial heterogeneity and its role in vascular growth.

1 citation

mousescRNA-seq

𝕏 PostBluesky