Author

Alex H. Y. Chan

University of CambridgeORCID 0009-0006-7897-4560Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Organism:plant (other)· 1

Frequent Co-Authors

Finian J. LeeperiD· 1 shared Imam FathoniiD· 1 shared Kai MatuschewskiiD· 1 shared Kevin J. SalibaiD· 1 shared Terence C. S. Ho· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperPharmacology & Toxicology

Finian J. LeeperORCID

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1 paper

Recent·Most cited

Pharmacology & ToxicologyAntimicrobial Agents and ChemotherapyPeer-reviewedOct 29, 2024

Identification and characterization of thiamine analogues with antiplasmodial activity

Imam Fathoni, Terence C. S. Ho, Alex H. Y. Chan…·Kevin J. Saliba

This study identifies N3-pyridyl thiamine (N3PT) as a more potent antiplasmodial thiamine analogue than oxythiamine, with lower toxicity to human cells and effective in vivo activity against malaria parasites.

6 citations

humanmouse

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