Author

Sitao Zhang

National Institute of Biological Sciences, BeijingORCID 0000-0002-2956-725XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Britt Tilkin· 1 shared Diana PioliD· 1 shared Don W. ClevelandiD· 1 shared Fátima Gasset-Rosa· 1 shared Hongbin LiuiD· 1 shared James ShorteriD· 1 shared Jia GuoiD· 1 shared Jianhua SuiiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Britt Tilkin

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2 papers

Recent·Most cited

PathologyProceedings of the National Academy of SciencesPeer-reviewedAug 23, 2024

LRG1 promotes atherosclerosis by activating macrophages

Juan Wang, Jing Wang, Jiuchang Zhong…·Xiaodong Wang

This study identifies LRG1 as a pro-inflammatory factor in atherosclerosis by promoting macrophage M1 polarization through ERK and JNK pathways, and shows that LRG1 inhibition reduces atherosclerosis progression.

42 citationstop 2%

mousebulk RNA-seq

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NeuroscienceMolecular NeurodegenerationPeer-reviewedJun 11, 2024

Frontotemporal dementia-like disease progression elicited by seeded aggregation and spread of FUS

Sonia Vazquez‐Sanchez, Britt Tilkin, Fátima Gasset-Rosa…·Sandrine Da Cruz

This study shows that injecting human FUS fibrils into mice with human FUS causes FUS aggregation and FTLD-like disease progression, with prion-like spread and cognitive deficits.

14 citations

mouseexperimental assay

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