Dubai Li

The paper introduces Seq2Kd, a deep learning model predicting TF-DNA binding affinity using high-throughput Kd measurements, and provides a web portal for functional genomics and disease research.

This paper quantifies binding cooperativity between adjacent transcription factors on DNA and identifies its functional roles in gene regulation.

The paper introduces a method to map transcription factor binding sites genome-wide with single-base resolution and applies it to study cell-type-specific TF cooperativity in human tissues.