Author
Icahn School of Medicine at Mount SinaiORCID 0009-0006-9988-0424Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
Recent·Most cited
Ana I. Hernández Cordero, Xuan Li, Chen Xi Yang…·Don D. Sin
The paper identifies co-expressed genes with ACE2 and TMPRSS2 in lung tissue and finds many have drug interactions, suggesting potential targets for COVID-19 therapeutics.
Dipender Gill, Marios Arvanitis, Paul Carter…·Stephen Burgess
This study uses Mendelian randomization to examine if ACE inhibitors or cardiometabolic risk factors affect lung ACE2 and TMPRSS2 expression or plasma ACE2 levels, finding no overall association.
Katherine A. Fawcett, Ma’en Obeidat, Carl Melbourne…·Louise V. Wain
The paper identifies SNPs with sex-specific effects on lung function traits using UK Biobank data, finding a significant interaction at rs7697189 near HHIP.
Richard J. Allen, Beatriz Guillén‐Guío, Justin M. Oldham…·Louise V. Wain
This study identifies three new genetic loci associated with idiopathic pulmonary fibrosis and confirms 11 previously reported ones, highlighting mTOR signaling and mitotic spindle-assembly genes in disease susceptibility.
Nick R. G. Shrine, Anna L. Guyatt, Abdullah Mesut Erzurumluoglu…·Andrew P. Morris
The paper identifies 279 new genetic signals for lung function across multiple ancestries, showing associations with COPD and pleiotropic effects.
Maxime Lamontagne, Jean‐Christophe Bérubé, Ma’en Obeidat…·Yohan Bossé
The paper identifies 12 novel COPD loci and candidate causal genes using GWAS and lung eQTL data from 129 risk loci.
Victoria E. Jackson, Jeanne C. Latourelle, Louise V. Wain…·Sven Gläser