Siyu Lin

SQUALL integrates histology and spatial transcriptomics to enable virtual spatial gene expression profiling and clinical prediction across cancers and platforms.

The paper presents an integrative spatial multi-omics atlas of female genital tumors, identifying prognostic tumor niches and developing a model to predict their abundance from histopathology.

This paper presents a method to directly produce and purify CRISPR/Cas RNP from E. coli in a single step using an ultra-high-affinity CL7/Im7 system, achieving high stability and genome editing efficiency.