Iris Zheng

This study determines the structure of human GluD1 and elucidates its ligand-gating mechanism using cryoEM and electrophysiology.

This study identifies a tripartite mechanism involving Imp7 and Imp1 that licenses RNA polymerase import into the phage nucleus, showing that nuclear compartment assembly precedes transcriptional and replicative programs.

The paper identifies dopamine as a direct agonist of GluDs, showing G-protein regulation of their activity and implications for neurological diseases.