Anish Kumar Mondal

This study determines the structure of human GluD1 and elucidates its ligand-gating mechanism using cryoEM and electrophysiology.

The paper identifies dopamine as a direct agonist of GluDs, showing G-protein regulation of their activity and implications for neurological diseases.

This study identifies PSA as an inhibitory auxiliary subunit of VRACs, showing its regulatory role is independent of aminopeptidase activity.

This study shows that glutamate gating of AMPA receptors is temperature sensitive and distinct from PAM-induced gating, revealing conserved structural motifs and desensitization mechanisms.