Evolutionary BiologybioRxivPreprint
Evidence for an energetic trade-off model linking inflammaging and immunosenescence in the US Health and Retirement Study and UK Biobank
Jacob E. Aronoff, Maximilien Franck, Alan Arthur Cohen, Benjamin C. Trumble
The paper examines an energetic trade-off model linking inflammaging and immunosenescence using data from the US Health and Retirement Study and UK Biobank, finding evidence of TNFR1 and GDF15 mediating age-related immune declines and health risks.
DOI 10.1101/2025.10.17.682903