Author

Patricia G. Webb

University of Colorado AnschutzORCID 0009-0007-0589-9018Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Benjamin Guy BitleriD· 2 shared Daniel Núñez-AvellanedaiD· 2 shared Elizabeth R. WoodruffiD· 2 shared Fabian R. VillagómeziD· 2 shared Julie LangiD· 2 shared Margaret Cobb NevilleiD· 2 shared Fredrick Joseph RosarioiD· 1 shared Hannah L. DimmickiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCancer Biology

Benjamin Guy BitlerORCID

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2 papers

Recent·Most cited

Cancer BiologyCancer Research CommunicationsPeer-reviewedDec 3, 2024

Claudin-4 remodeling of nucleus-cell cycle crosstalk maintains ovarian tumor genome stability and drives resistance to genomic instability-inducing agents.

Fabian R. Villagómez, Julie Lang, Daniel Núñez-Avellaneda…·Benjamin Guy Bitler

This paper shows that claudin-4 remodels nucleus-cell cycle interactions to maintain genome stability and resist genomic instability-inducing agents in ovarian cancer.

6 citations

humanexperimental assay

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Cancer BiologyCancer Research CommunicationsPeer-reviewedJun 13, 2024

Claudin-4 modulates autophagy via SLC1A5/LAT1 as a tolerance mechanism for genomic instability in ovarian cancer.

Fabian R. Villagómez, Julie Lang, Fredrick Joseph Rosario…·Benjamin Guy Bitler

This study shows claudin-4 promotes genomic instability tolerance in ovarian cancer by linking cell junctions to autophagy via SLC1A5/LAT1, and targeting it enhances PARPi efficacy.

10 citations

humanproteomics

𝕏 PostBluesky