Author

Huijin Lee

Boston Children's HospitalORCID 0009-0007-1261-0139Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Fahad RashidiD· 1 shared James Andrew LondoniD· 1 shared James M. BergeriD· 1 shared Jihee HwangiD· 1 shared Richard A. FisheliD· 1 shared Sua MyongiD· 1 shared Taekjip HaiD· 1 shared

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1 shared paperBiophysics

Fahad RashidORCID

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1 paper

Recent·Most cited

BiophysicsNucleic Acids ResearchPeer-reviewedJun 10, 2025

A high throughput single molecule platform to study DNA supercoiling effect on protein-DNA interactions

Huijin Lee, Fahad Rashid, Jihee Hwang…·Taekjip Ha

The paper develops a single-molecule platform to study DNA supercoiling effects on protein-DNA interactions, finding that negative supercoiling increases Cas9 off-target effects and enhances MutS binding to mismatched bases.

8 citations

DNA methylationexperimental assay

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