Author

Lewis Hitchens

University of British ColumbiaORCID 0009-0007-1503-7286Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2

Signature Assays, Organisms & Methods

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Organism:yeast· 2 Assay:DNA methylation· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Corey NislowiD· 2 shared Guri N. GiaeveriD· 2 shared Hamid Kian GaikaniiD· 2 shared Marjan BarazandehiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersGenomics

Corey NislowORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintOct 3, 2026

Defining the spectrum of cellular protection against cadmium stress by Dsup expressed in yeast

Lewis Hitchens, Hamid Kian Gaikani, Marjan Barazandeh…·Corey Nislow

The paper identifies host genetic processes that influence Dsup's ability to confer cadmium resistance in yeast by screening deletion mutants under cadmium stress.

DOI 10.64898/2026.09.28.755128

yeastexperimental assay

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GenomicsbioRxivPreprintDec 25, 2025

Friend and Foe: Genome-Wide Analysis of the Tardigrade Dsup Protein Expressed in Yeast Reveals Trade-offs of DNA Protection

Hamid Kian Gaikani, Marjan Barazandeh, Lewis Hitchens…·Corey Nislow

This study shows that Dsup protects yeast from DNA damage but has fitness costs and creates new dependencies on DNA repair pathways.

DOI 10.64898/2025.12.24.696340

yeastDNA methylation

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