Author

Zhicong Liao

Icahn School of Medicine at Mount SinaiORCID 0009-0007-2060-8290Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genomics· 2 Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:differential expression· 3 Assay:DNA methylation· 3 Organism:human· 3 Assay:ATAC-seq· 2 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

Bohan ZhuiD· 3 shared Sai MaiD· 3 shared Zhe Wang· 3 shared Elvin WagenblastiD· 2 shared John F. FullardiD· 2 shared Mimi ZhangiD· 2 shared Panos RoussosiD· 2 shared Agata KurowskiiD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersGenomics

Bohan ZhuORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

NeurosciencebioRxivPreprintNov 11, 2026

Tri-Modal Single-Cell Atlas of Developing Human Brain

Liting Song, Zhe Wang, Bohan Zhu…·Sai Ma

The paper maps gene expression, chromatin accessibility, and DNA methylation in developing human brain cells to understand regulatory interactions and their role in disease.

DOI 10.64898/2026.11.10.765750

humanscRNA-seq

𝕏 PostBluesky

GenomicsbioRxivPreprintOct 11, 2026

Disrupted chromatin architecture blocks B lymphopoiesis in Down syndrome

Zhicong Liao, Mimi Zhang, Brian Y. Soong…·Sai Ma

The paper develops ChromE-seq to study 3D chromatin architecture in fetal hematopoiesis, finding that T21 disrupts B-lineage development by altering chromatin connectivity and regulatory circuits.

DOI 10.64898/2026.10.07.757425

humanChIP-seq

𝕏 PostBluesky

GenomicsbioRxivPreprintFeb 2, 2026

Early microglial priming in Alzheimer's disease revealed by ME-seq

Bohan Zhu, Anurupa Ghosh, Zhe Wang…·Sai Ma

The paper introduces ME-seq, a technology that profiles DNA methylation, gene expression, and chromatin accessibility in single nuclei, revealing early microglial priming in Alzheimer's disease.

4 citations

mouseDNA methylation

𝕏 PostBluesky

GeneticsbioRxivPreprintMar 21, 2025

H3K4me3 instructs transcription at intergenic active regulatory elements

Haoming Yu, Yongyan Zhang, Zhicong Liao…·Bluma J. Lesch

The paper investigates the role of H3K4me3 at intergenic regulatory elements and finds it instructs RNA polymerase activity and is actively remodeled.

1 citation

humanChIP-seq

𝕏 PostBluesky