Author
Icahn School of Medicine at Mount SinaiORCID 0000-0003-4647-7704Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Zhicong Liao, Mimi Zhang, Brian Y. Soong…·Sai Ma
The paper develops ChromE-seq to study 3D chromatin architecture in fetal hematopoiesis, finding that T21 disrupts B-lineage development by altering chromatin connectivity and regulatory circuits.
Raphaël Mattiuz, Jesse Boumelha, Emmanouil Aerakis…·Miriam Mérad
This study identifies the role of mature dendritic cells type 1 in forming, maintaining, and functioning tertiary lymphoid structures in cancer.
Samarth Hegde, Bruno Giotti, Brian Y. Soong…·Miriam Mérad
The paper identifies NRF2-driven myeloid progenitor dysregulation that sustains immunosuppressive macrophages in tumors, showing NRF2 inhibition reduces their survival and enhances antitumor immunity.
Pauline Hamon, Matthew D. Park, Jessica Le Bérichel…·Miriam Mérad
The paper identifies TREM2-expressing macrophages as predictors of response to PD-1 blockade in HCC patients using clinical and spatial transcriptomic data.
Rebecca J. Carlson, J. J. Patten, George Stefanakis…·Paul C. Blainey
This study uses single-cell image-based CRISPR screens to identify host factors regulating Ebola virus infection, revealing new therapeutic targets like UQCRB and STRAP.