Jenny Johansson

This study shows that activating ERV-W in human glutamatergic neurons disrupts postsynaptic organization and synaptic function.

The paper investigates TE transcription in Parkinson's disease brains, finding region- and cell-type-specific TE activation linked to an interferon response in microglia and neurons.

This study reprograms human dental pulp stem cells into neurons more rapidly and efficiently than fibroblasts, using a lentiviral vector and single-nucleus RNA sequencing to characterize the process.

This study shows that loss of H3K9me3 in human neural progenitor cells activates L1 retrotransposons by reducing CpG methylation at their promoters.

This study identifies a chimpanzee-specific retroviral insertion that influences gene regulation and brain development, highlighting its role in human-chimpanzee brain divergence.

The paper develops cell-type-specific transcriptomic aging clocks using single-nuclei RNA sequencing data from human prefrontal cortex tissue, showing distinct aging patterns across cell types.

This study shows that L1 retrotransposons influence human pluripotency exit and early brain development through their expression and derived transcripts.

This study shows MORC2 regulates CpG methylation of active LINE-1 retrotransposons during human neurodevelopment, similar to the piRNA pathway in the germline.

The paper identifies a human-specific structural variation at the ZNF558 locus that regulates a gene network involved in forebrain development by controlling SPATA18 expression through a VNTR contraction.