Author

Irene Sala

ETH ZurichORCID 0009-0007-2577-9523Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Jacob E. CorniD· 2 shared Ana GvozdenoviciD· 1 shared András TálasiD· 1 shared Charles D. YehiD· 1 shared Danielle N. GallagheriD· 1 shared F. V. Gorbenko· 1 shared Gerald SchwankiD· 1 shared Gytis DruteikaiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBioengineering

Jacob E. CornORCID

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2 papers

Recent·Most cited

BioengineeringGenome biologyPeer-reviewedJun 16, 2026

Directed evolution of compact RNA-guided nucleases for enhanced activity in mammalian cells

F. V. Gorbenko, Irene Sala, Young-Yoon Lee…·Jacob E. Corn

The paper improves the activity of compact RNA-guided nucleases in mammalian cells through directed evolution, resulting in variants with higher editing efficiency and reduced off-target effects.

2 citations

humanexperimental assay

𝕏 PostBluesky

GenomicsbioRxivPreprintMay 24, 2026

Predicting cellular functions of human phosphosites

Julian van Gerwen, Danielle N. Gallagher, Irene Sala…·Pedro Beltrão

The paper develops predictors to functionally characterize human phosphosites using integrated data, revealing novel functions and connections to DNA repair and cell survival.

DOI 10.64898/2026.05.22.727149

humanproteomics

𝕏 PostBluesky