Author

Arvind Parate Shivani

Indian Institute of Technology HyderabadORCID 0009-0007-3311-2542Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Eerappa RajakumaraiD· 1 shared Makwana MileeiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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2 top collaborators · 1 mutual co-author link

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1 shared paperBiochemistry

Eerappa RajakumaraORCID

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1 paper

Recent·Most cited

BiochemistryFEBS JournalPeer-reviewedJul 21, 2026

Allosteric activation of PARP2 self-PARylation by SUMO constrains DNA break-dependent catalytic Function

Arvind Parate Shivani, Makwana Milee, Eerappa Rajakumara

This study shows SUMO binds to PARP2, enhancing its self-PARylation but reducing DNA-dependent catalytic activity, revealing a new regulatory mechanism in DNA repair.

1 citation

humanproteomics

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