Author

Makwana Milee

Indian Institute of Technology HyderabadORCID 0009-0002-1633-2176Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:Arabidopsis· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Eerappa RajakumaraiD· 2 shared Anamika BhargavaiD· 1 shared Arvind Parate ShivaniiD· 1 shared Ghazala RahmaniD· 1 shared Shambhavi Khare· 1 shared Shanavas P GreeshmaiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 11 mutual co-author links

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2 shared papersBiochemistry

Eerappa RajakumaraORCID

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2 papers

Recent·Most cited

Evolutionary plasticity of regulatory--catalytic coupling in mono- and poly-ADP-ribosyl transferases

Makwana Milee, Shambhavi Khare, Shanavas P Greeshma, Ghazala Rahman, Anamika Bhargava, Eerappa Rajakumara

The paper investigates how regulatory and catalytic domains of ADP-ribosyltransferases co-evolve, showing functional complementarity across species and enzyme classes.

bioRxiv · Oct 19, 2026 · PreprintBiochemistry

Allosteric activation of PARP2 self-PARylation by SUMO constrains DNA break-dependent catalytic Function

Arvind Parate Shivani, Makwana Milee, Eerappa Rajakumara

This study shows SUMO binds to PARP2, enhancing its self-PARylation but reducing DNA-dependent catalytic activity, revealing a new regulatory mechanism in DNA repair.

FEBS Journal · Jul 21, 2026Peer-reviewedBiochemistry