Author

Alexandra Kovinko

Leibniz-Forschungsinstitut für Molekulare PharmakologieORCID 0009-0007-3664-0594Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Assay:cryo-EM· 1 Organism:E. coli· 1 Approach:microscopy & imaging analysis· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Adam LangeiD· 2 shared Antonia M Körber· 1 shared Arbesa Saiti· 1 shared Blaise Gatin‐FraudetiD· 1 shared Carl ÖsteriD· 1 shared Carlos A. Elena‐RealiD· 1 shared Chaowei ShiiD· 1 shared Daniel RodereriD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiophysics

Adam LangeORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintAug 25, 2026

Emergence of new function through evolutionary divergence of an intrinsically disordered region

Carlos A. Elena‐Real, Antonia M Körber, Blaise Gatin‐Fraudet…·Sigrid Milles

This study shows how transient secondary structure in intrinsically disordered regions can generate new molecular functions while preserving ancestral activities in paralogous proteins.

DOI 10.64898/2026.08.25.746950

protein structureexperimental assay

𝕏 PostBluesky

BiophysicsbioRxivPreprintApr 15, 2026

Atomic structure and dynamics of the mechanosensitive channel MscL from E. coli by cryo-EM and solid-state NMR

Taoran Xiao, Alexandra Kovinko, Chaowei Shi…·Adam Lange

This study uses cryo-EM and solid-state NMR to determine the structure and dynamics of MscL from E. coli, revealing lipid-protein interactions that drive mechanosensitive gating.

1 citation

E. colicryo-EM

𝕏 PostBluesky