Author

Ido Calman

ORCID 0009-0007-4177-4415Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Assay:protein sequence· 2 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Sharrol T. BachasiD· 2 shared Alec Jaeger· 1 shared Alyssa Ruelos· 1 shared Amir Shanehsazzadeh· 1 shared Audree Feltner· 1 shared Breanna K. Luton· 1 shared Brooke Stoddard· 1 shared Cailen M. McCloskey· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioengineering

Sharrol T. BachasORCID

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintDec 27, 2025

Iterative Epitope Expansion Enables Structure-Guided de novoDesign of IgE-Binding Miniproteins Targeting the FcεRI Interface

Ido Calman, Hamed Shaykhalishahi, Puwanat Sangkhapreecha, Sharrol T. Bachas

This paper develops an iterative epitope-expansion strategy to design IgE-binding miniproteins targeting the FcεRI interface, improving affinity and validating structural models through experimental testing.

DOI 10.64898/2025.12.27.696647

humanprotein structure

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Synthetic BiologybioRxivPreprintDec 8, 2023

IgDesign: In vitro validated antibody design against multiple therapeutic antigens using inverse folding

Amir Shanehsazzadeh, Julian Alverio, George W. Kasun…·Sharrol T. Bachas

IgDesign designs antibody CDRs using deep learning and validates them in vitro, showing high success rates and improved affinities for multiple therapeutic antigens.

28 citations

protein sequencedeep learning

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