Author

Adam Groth

Duke UniversityORCID 0009-0007-4317-224XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Avneesh SaravanapavaniD· 1 shared Joshua Tolliver· 1 shared Lixia Luo· 1 shared Loren B. WeidenhammeriD· 1 shared Matthew S. WaitkusiD· 1 shared Nerissa T. WilliamsiD· 1 shared Sheeba JacobiD· 1 shared Spencer M. Maingi· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Avneesh SaravanapavanORCID

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1 paper

Recent·Most cited

GeneticsNeuro-Oncology PediatricsPeer-reviewedMar 16, 2026

Oncogenic Ppm1d mutations deregulate the p53 pathway in primary mouse gliomas

Vennesa Valentine, Adam Groth, Joshua Tolliver…·Zachary J. Reitman

This study develops a mouse model of Ppm1d mutations in gliomas, showing they deregulate the p53 pathway, promote gliomagenesis, and increase radiosensitivity and PARP inhibitor vulnerability.

DOI 10.1093/neuped/wuag012

mousebulk RNA-seq

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