Author

Zachary J. Reitman

Duke UniversityORCID 0000-0002-9122-9550Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

Adam GrothiD· 1 shared Andrew Thompson· 1 shared Anna L. Price· 1 shared Avneesh SaravanapavaniD· 1 shared Denise Dunn· 1 shared Eric L. MartiniD· 1 shared Joshua Tolliver· 1 shared Lixia Luo· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperGenetics

Adam GrothORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Oncogenic Ppm1d mutations deregulate the p53 pathway in primary mouse gliomas

Vennesa Valentine, Adam Groth, Joshua Tolliver, Avneesh Saravanapavan, Spencer M. Maingi, Loren B. Weidenhammer, Nerissa T. Williams, Lixia Luo, Matthew S. Waitkus, Sheeba Jacob, Zachary J. Reitman

This study develops a mouse model of Ppm1d mutations in gliomas, showing they deregulate the p53 pathway, promote gliomagenesis, and increase radiosensitivity and PARP inhibitor vulnerability.

Neuro-Oncology Pediatrics · Mar 16, 2026Peer-reviewedGenetics

Investigating Rat-Brain Normal Tissue and Tumor FLASH Effects with a Novel Very High Energy Electron Beam

Tyler V. Kay, Anna L. Price, Markus Sprenger, Victoria J. P. Radosova, Andrew Thompson, Eric L. Martin, Denise Dunn, V. Popov, S.F. Mikhailov, Zachary J. Reitman, Y. Wu, Scott Floyd, Mark Oldham

This study investigates FLASH radiation effects on rat brain tissue and tumors using a novel high-energy electron beam, finding differential immune responses and microglial changes.

bioRxiv · Sep 5, 2025 · PreprintCancer Biology