PhysiologyeLifePeer-reviewed
The Kv2.2 channel mediates the inhibition of Prostaglandin E2 on glucose-stimulated insulin secretion in pancreatic β-cells
Chengfang Pan, Ying Liu, Liangya Wang…·Changlong Hu
This study shows PGE2 inhibits glucose-stimulated insulin secretion in β-cells via the EP2/4-Kv2.2 pathway by modulating Kv2.2 channels through PKA.