Author

Danielle Keahi

Rockefeller UniversityORCID 0009-0007-4545-1429Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Agata SmogorzewskaiD· 2 shared Tom F. WileyiD· 2 shared A. L. H. Webster· 1 shared Audrey M. GoldfarbiD· 1 shared Carolina Sandoval-GarciaiD· 1 shared Claudia WongiD· 1 shared Fan YangiD· 1 shared Francis P. LachiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Agata SmogorzewskaORCID

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2 papers

Recent·Most cited

Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewedAug 25, 2025

G-quadruplexes are a source of vulnerability in BRCA2 deficient granule cell progenitors and medulloblastoma

Danielle Keahi, Mathijs Arnoud Sanders, Matthew Robert Paul…·Agata Smogorzewska

This study identifies G-quadruplexes as a source of genome instability in BRCA2-deficient granule cell progenitors and medulloblastoma, suggesting PIF1 helicase as a therapeutic target.

2 citations

mousewhole-genome sequencing

𝕏 PostBluesky

GeneticsThe Journal of Cell BiologyPeer-reviewedMay 3, 2025

ALDH9A1 Deficiency as a Source of Endogenous DNA Damage that Requires Repair by the Fanconi Anemia Pathway

Moonjung Jung, Jung-Woo Kim, Yeji Park…·Agata Smogorzewska

The paper identifies ALDH9A1 deficiency as a source of endogenous DNA damage that requires FA pathway repair, leading to genomic instability and tumorigenesis in FA-deficient cells.

13 citations

mouseexperimental assay

𝕏 PostBluesky