Cell BiologybioRxivPreprint
Actin Networking Collapse Under STAT5A Deficiency Drives Mitochondrial Dysfunction and Autocrine IFN-beta Production
Boyue Sun, Mathumathi Krishnamohan, Reinat Nevo…·Gideon Schreiber
This paper shows that STAT5A deficiency disrupts actin networks, leading to mitochondrial dysfunction and IFN-beta production, which can be reversed by restoring ACTN1.
DOI 10.1101/2025.05.26.656095