Didier Debrincat

This study shows that reducing versican in dystrophic mdx hindlimb muscles improves contractile function in juvenile mice without reducing inflammation, but these benefits are lost in adults.

This study shows that moderate-term dimethyl fumarate treatment reduces dystrophic muscle pathology in a mouse model of Duchenne muscular dystrophy, with anti-inflammatory, anti-fibrotic, and anti-lipogenic effects.

This study shows that estrogen loss in female mdx mice reduces exercise capacity and mitochondrial metabolism, but estrogen replacement therapy can reverse these effects and upregulate Rbm20.