Exploring the Structural and Functional role of α,β-unsaturated Ketoesters as Anti-Staphylococcal Agents Targeting Glutathione Peroxidase
Sushobhan Maji, Sayoni Dam, Akanksha Kumari…·Sudipta Bhattacharyya
This study identifies SaGpx as a virulence factor in S. aureus and develops β-unsaturated ketoester inhibitors that block its activity, showing antibacterial and wound healing effects in vivo.